Dean Donny Huijsen Wijsmuller (ডিন হইসেন) is a professional footballer who plays as a centre-back for La Liga club Real Madrid. Born in the Netherlands, he plays for the Spain national team.

Huijsen made his senior debut for Juventus's reserve team Juventus Next Gen in January 2023, and made his Serie A debut with the first team the following October. Following a loan spell at Roma, Huijsen signed for Premier League side Bournemouth in July 2024. One year later, he moved to La Liga club Real Madrid.

Huijsen was born in Amsterdam to Macha Wijsmuller and Donny Huijsen. Dean's father Donny played for Jong Ajax and had a professional career in the Eredivisie and the Eerste Divisie. Dean can speak Dutch, Spanish, Italian and English. The family relocated to Marbella, Andalucía, Spain when he was five years old; he became a Spanish citizen in February 2024. Huijsen's idol growing up was the defender Sergio Ramos.

Huijsen has represented the Netherlands at various youth international levels, having played for the under-17 and under-18 national teams.

In May 2022, Huijsen was included in the Dutch under-17 squad that took part in the UEFA European Under-17 Championship in Israel, where he scored two penalties in the group stage matches against France and Poland, as Oranje eventually finished as runners-up after losing to France itself in the final.

On 15 March 2024, Huijsen was called up by the Spain national under-21 team to play the 2025 UEFA European Under-21 Championship qualification Group B match against Belgium twelve months later. On 17 March 2025, he was called up by the senior side for the Nations League quarter-finals against the Netherlands. He was covering Iñigo Martínez's absence due to injury and made his debut coming on in the 41st minute, replacing Pau Cubarsí. The match ended 2–2, Huijsen was one of Spain's best players and received a hostile reception from home fans in the Stadion Feijenoord for switching nations in order to play for Spain. He called his debut a "dream." Huijsen started the second leg and was praised for an assist in additional extra time which Lamine Yamal scored from.

Huijsen is a physical 1.96 m-tall centre-back. He is mainly right-footed but can also use his left foot. He has an eye for the goal and can also take penalty kicks.